What Are ADHD Clinical Trials?

ADHD imageADHD is a commonly diagnosed developmental disease, yet it is also a misunderstood condition. According to a 2021 study, ADHD affects around 5% of children and adolescents worldwide. However, myths about ADHD are widespread, and they can impact people’s perception, or discourage people from getting help.

When beliefs and stigma obstruct therapy, people’s lives can be threatened. ADHD coexists with other mental health issues, and some evidence suggests there may be a link between the two. According to another study, ADHD in children increased the likelihood of depression and anxiety in maturity. 

Thankfully, there are various treatments available for ADHD, and clinical trials are being done worldwide to combat the condition. 


What Are Clinical Trials?

Clinical trials evaluate the safety and efficacy of various medications for people with certain conditions, and are the quickest and safest way to find effective treatments. Researchers examine the potential treatment, its dangers, how well it might or might not work, and quality of life issues throughout the trial.

How Do Clinical Trials Work?

The volunteers receive treatment in a clinical study, and researchers examine how the treatment affects them. Throughout the trial, the patient or volunteer’s progress is continuously observed. Various treatments and medications are used to identify which works best. Researchers may remain monitoring patients after the treatment component of the trial is done to gain more information regarding the treatment’s effects.

ADHD Clinical Trials


There have been numerous trials for diagnosing and treating ADHD in children. Examples of ADHD clinical trials include:

  • Children’s pharmacological treatment 
  • Behavioral treatment
  • Digital treatment
  • Combined treatment trials 

Some pediatric clinical trials look into the impact of lead exposure, other neurotoxins, and psychosocial conditions (which include aspects of social and psychological behavior) in the development of ADHD. 

Phases of Clinical Trials

Clinical studies are divided into four phases, each with its own goal. 

Phase I 

In phase I, new treatment or medicine is given to a limited group of volunteers. The researchers determine the best technique to administer the new medication and how much of it is safe to administer. Phase I trials are also conducted in healthy individuals to determine a treatment’s safety. 


Phase II 

Phase II is used to see if a novel medication works for a specific ailment. Additional information about the treatment’s side effects is also obtained. 

Phase III

In phase III, the new treatment is compared to a standard or placebo treatment. Researchers decide which trial group has the fewest adverse effects and shows the best improvement in this phase. 

Phase IV


After a treatment has been licensed, phase IV clinical trials are done. This phase aims to learn more about the medication and to answer any questions that may have emerged during the trial’s prior rounds. This phase includes a larger number of participants and may disclose previously unreported side effects.

How Can I Find ADHD Clinical Trials to Join?

The best place to start your clinical trial search is online, such as searching for ADHD clinical trials on the Power website.

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